Research has shown that there are four main causes of fibromyalgia syndrome:

genetic predisposition

hypothalmic-pituitary-adrenal axis dysregulation

pain processing systems

behavioral and psychological factors


Hypothalmic, Pituitary and Adrenal Hormones

The human body has a well defined set of emergency procedures to deal with stressors.  The efficacy of these emergency procedures is dependent on how efficiently the hormones relay messages to the brain.

The system links the mind and the body.

Stress alters blood flow and muscle metabolism.

In FMS there is less secretion of stress coping hormones.

In FMS the circadian rhythms are out of balance resulting in hormone secretion malfunctioning.

Adrenal Insufficiency

Low Cortisol

low blood pressure

low blood sugar


poor immune system

inability to deal with stress



Low Aldosterone

body loses the ability to keep the salt and water in balance


Low Estrogen and Testosterone

poor libido



In Summary:

severe, chronic pain

pituitary overstimulation
(from excess electrical current)

release of ACTH (from pituitary)

adrenal stimulation

excess release of adrenalin and cortisol
(possibly resulting in hyperlibidemia, hyperglycemia, obesity, osteoporosis poor pain control)

tachycardia, hypertension, high serum cortisol

with time and uncontrolled pain

adrenal exhaustion
(low serum cortisol, "vegetative state", extreme fatigue)

Mariposa Dreams

Plymouth Integrative Medicine Center
Fibromyalgia Doctor ~ Irene Metro MD
44670 Ann Arbor Rd, Ste 100, Plymouth, MI 48170

Call 734.432.1900 for an appointment with Fibromyalgia Doctor ~ Irene C. Metro MD

The information contained on this web site is not intended to treat, diagnose, cure or prevent any disease, nor is it intended to replace proper medical care. All material provided in this web site is provided for educational purposes only. Always seek the advice of your physician or other qualified health care provider with any questions you have regarding a medical condition, and before undertaking any diet, exercise or other health program.

Fibromyalgia doctor Irene C. Metro, MD, Board Certified Internal Medicine, Board Certified American Board of Integrative & Holistic Medicine, is the medical director of the Plymouth Integrative Medicine Center in Livonia, Michigan. This medical clinic has internal medicine, integrative medicine, physical therapy, acupuncture, lifestyle coaching, nutritional counseling, and psychotherapy, and specializes in fibromyalgia, chronic fatigue syndrome, hypertension, high blood pressure, insomnia, anxiety, depression, chronic pain, trigger point therapy, vitamin therapy, and pain relief. This medical clinic is located across from St. Mary Mercy Hospital and is easily accessible from Plymouth, Livonia, Canton, Northville, Redford, Westland, Farmington Hills, Southfield, Dearborn Heights, and other locations in Oakland County and Wayne County Michigan. Call 734-432-1900 to make an appointment with the fibromyalgia doctor MI today!